Relationship between Testosterone Hormone and Cholesterol



Testosterone hormone is a hormone which is responsible for secondary characteristics in males. However, it does occur in small quantities in females. Testosterone hormone is a derivative of cholesterol.  In which the hydroxyl group (-OH) attached to carbon number three of the first ring of the cholesterol is oxidized to a carbonyl group (-C=O). The double (between carbon number five and six) in the second ring of cholesterol is shifted to the first between carbon number four and five in the chemical structure of testosterone hormone. The alkyl group substituted at carbon number seventeen of cholesterol is replaced with the hydroxyl group during the formation of testosterone hormone.  From the cholesterol chemical structure, it is observed that eight carbon atoms, eighteen hydrogen atoms are lost, and the oxygen atom is added during the formation of testosterone hormone.
Testosterone hormone is endocyclic(has double bond within a ring), has extended conjugation, absorbs ultraviolet light at 277nm, and has chemical formula C19H2802 with a molecular weight of 288g/mole.The chemical structures of testosterone hormone and cholesterol are given below: 
                                   Fig 1: Testosterone hormone 
                                                Fig 2: Cholesterol

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